Dangling Man was the first novel published by Nobel Prize winner Saul Bellow. It was published in 1944 by Vanguard Press, and which today is owned by Random House. The novel forms a diary kept by Joseph for a one year: December 15, 1942, through to April 9 1943. The very first entry begins with the caveat that although to keep a diary is not something that should be done – since one should...
The Algebraist (BR)
The Algebraist is a science fiction novel set in the unfathomably far future and is penned by the established author Iain M. Banks. The plot concerns a star system being attacked by some force, (I would have written “alien force” but by this stage in the universe’s history to define something as an alien is rather provincial). The attack is motivated by a desire to conquer the...
LINE-1 retrotransposition in neurons
LINE-1 retrotransposons are sections of DNA which are capable of copying themselves into another part of the genome. Although traditionally considered to merely epitomize the concept of the selfish gene, more recently they have been suggested to have physiological functions. Here I discuss the incredibly fascinating hypothesis that LINE-1 retrotransposons may be important in generating neuronal...
Dawkins’ God
Dawkin’s God is a non-fiction book by Alister McGrath published in 2004. It is a response to Dawkin’s views, especially as they regard religion. The book is subtitled Genes, Memes, and the Meaning of Life. Comments: The most intelligible interpretation of McGrath’s take on Dawkins is that Dawkins is attacking academic-religion and not pop-religion. The reason for making this...
Jesus’ Son by Denis Johnson (BR)
Jesus’ Son is a collection of stories revolving around a lost soul known as fuckhead. The book was published in 1992, and in 1999 was made into a movie by the same name. The book’s title comes from The Velvet Underground‘s song Heroin. When I’m rushing on my run And I feel just like Jesus‘ son… Comments: While the main theme (or at least thematic motif) found...
A meditation on Plato’s Ion
Plato was an Ancient Greek philosopher who lived around 2400 years ago in Athens. Almost all of Plato’s surviving writings are dialogues (philosophical plays). Ion is a dialogue between Socrates (Plato’s teacher) and Ion, a celebrated performer of poetry. Although Plato is always interesting, it is often hard to find a positive lesson that can be drawn from his philosophy. Often his...
Nicotine receptors and depression
This is a summary of a review-piece published in the prestigious science journal Trends in Pharmacological Sciences in 2010 ([link]) entitled “Nicotine receptors and depression: revisiting and revising the cholinergic hypothesis“. The publication was authored by Yann Mineur and Marina Picciotto and discussed the connection between smoking, nicotinic receptors, and depression. Below I...
Reflections on the Human Condition
Three books collide in my mind and make me reflect on the human condition. Please excuse me. 1. T.S. Eliot wrote that April is the cruellest month because it reminds us of renewal; once, long ago, a woman asked the gods for immortality but forgot to ask for eternal youth. She begs to die and the renewal of spring in April taunts her. 2. Jorge Luis Borges, who was undoubtedly intimately familiar...
Ancient Greek Philosophy
What is this? It’s an index of sorts, linking to nodes that relate to philosophy in Ancient Greece. See also the first footnote below[1]. It was written for two main reasons: (1) As an index that can be referred to when looking for something to read about Ancient Greek philosophy; (2) as an index that can be referred to when trying to decide what has and hasn’t been written and what...
Biotinylation
Editorial notes: In November 2010, Shai begins the second phase of his intellectual journey with an essay dedicated to scientific summation. Throughout 2010 Shai’s writings are focused primarily on book reviews with the occasional venture into reviews of science. This focus shifts in 2013 when Shai produces 24 science-related compilations. Between November 2010 and June 2016, Shai produces 60...