There should be no doubt in the mind of the reflective sapiens that their biological basis is the least likely and most astounding object within all that they have known or imagined. But why? I force the reader to expand this sense of astonishment by (before leaping into a strict series of educational demonstrations) illustrating some elements that comprise their unarticulated amazement.<\/p>\n
How does the brain found your conscious experience? Let\u2019s assume that on one hand, the brain maps, encodes, and calculates all the information that forms the basis for those experiences, whether sensory, conceptual, or other. And on the other hand, let\u2019s assume that the brain creates eddies in some unknown ether, that the brain is manipulating some attribute of reality that already exists, and contorting that generalized consciousness, into the consciousness of the individual. Given those two assumptions, how does the brain correlate the physical and non-conscious facts within itself, with the subjective and conscious powers within itself? How is meaning brought to life?<\/p>\n
How does DNA encode for the entire human being? How can a series of chemical strings create an embryo, divide it into arms and muscles and eyes and what is above and inside and in between and younger and then older and sometimes dying and sometimes born? On one hand, let\u2019s assume that the DNA is a series of blueprints for all the decision-makers that can deal with the variegations of life. And on the other hand, let\u2019s assume that the DNA is capable of being by the decision-makers that surround it, knowing where to seek further advice, and how to act upon its wisdom. Given those two assumptions, how does the information – abstracted from the DNA – exist in a static form inside the DNA, such that it can teach its creations to read itself? If the DNA teaches the teachers, who teaches the DNA to teach?<\/p>\n
How does the single-cell embryo become a recognizable individual? How can something that is singular, without divisions, divide into all its parts? Let\u2019s assume on one hand, that there is an ability to coordinate between all the divisions and changes – perhaps within the DNA – that acts like an overseer in principle even if not literally. And let\u2019s assume on the other hand, that every newly divided cell contains the same potential as all others, capable in principle (even if not pragmatically) of becoming an entire individual by itself. Given those two assumptions, how do dividing cells obey a single command structure, without any command structure existing amongst them?<\/p>\n
The point of those three wonderings was to expand, even if only slightly, three particular axes for application: biology correlates meaning; biology correlates meaning between encodings and environments; biology disperses self-awareness amongst localized capacities for comparison. I\u2019ll raise and explain these below.<\/p>\n
First:<\/p>\n
Explain how chance can create a single voice. E.g. of notch\/delta.<\/p>\n
Explain how epigenetics annotates descendants. E.g. acetylation.<\/p>\n
Explain how morphogen gradients can create an array of instructions, first in general between two recipients, and then imagined with epigenetics determining reception.<\/p>\n
Explain how a single blueprint for structural division can be used across manifestations by receiving locally determined corollary instructions. E.g. hox genes.<\/p>\n
Explain how a single cell can become two different types according to epigenetics.<\/p>\n
Explain how the change from embryonic stem cells to differentiated cell type occurs along a gradient of cell fate.<\/p>\n
Now repeat but imagine that one has a single-family which needs to become a functional city.<\/p>\n
Now repeat but imagining a single domain of knowledge which needs to become modern knowledge.<\/p>\n","protected":false},"excerpt":{"rendered":"
There should be no doubt in the mind of the reflective sapiens that their biological basis is the least likely and most astounding object within all that they have known or imagined. But why? I force the reader to expand this sense of astonishment by (before leaping into a strict series of educational demonstrations) illustrating […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[159,206,154,16,83],"tags":[],"metadata":[],"class_list":["post-979","post","type-post","status-publish","format-standard","hentry","category-all-posts","category-biology","category-google-drive","category-science","category-study"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack-related-posts":[{"id":1175,"url":"https:\/\/thetravellerslastjourney.com\/shai\/2014\/09\/15\/similar-brain-across-bios\/","url_meta":{"origin":979,"position":0},"title":"Similar Brain Across Bios","author":"Pala","date":"September 15, 2014","format":false,"excerpt":"There\u2019s a great new study that shows how similar vertebrates\u2019 and insects\u2019 brains are. The scientists conduct molecular, developmental, genetic, and structural\/morphological, neurochemical, neurological, and higher-order function tests! So maybe that\u2019s cool1, but no real surprise2 1. It\u2019s actually super amazing cool. 2. Well, not to someone with a reasonable\u2026","rel":"","context":"In "All Posts"","block_context":{"text":"All Posts","link":"https:\/\/thetravellerslastjourney.com\/shai\/all-posts\/"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":2433,"url":"https:\/\/thetravellerslastjourney.com\/shai\/2014\/02\/13\/neurobiology-of-love\/","url_meta":{"origin":979,"position":1},"title":"Neurobiology of love","author":"Pala","date":"February 13, 2014","format":false,"excerpt":"This is\u00a0for\u00a0you. I\u00a0love\u00a0you. Love\u00a0is the quintessential\u00a0romantic,\u00a0irrational,\u00a0human\u00a0experience. It is in the first place the domain of its\u00a0clients, although readily owned by the\u00a0poets. As for others. The philosophers are permitted access, though they often regress into poets too; describing love as sacred,\u00a0profound, and utterly existential. In the penultimate place in the line\u2026","rel":"","context":"In "All Posts"","block_context":{"text":"All Posts","link":"https:\/\/thetravellerslastjourney.com\/shai\/all-posts\/"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":2397,"url":"https:\/\/thetravellerslastjourney.com\/shai\/2012\/07\/20\/molecular-biology-of-lithium-treatment-for-bipolar-effective-disorder-2\/","url_meta":{"origin":979,"position":2},"title":"Molecular biology of lithium treatment for bipolar effective disorder","author":"Pala","date":"July 20, 2012","format":false,"excerpt":"Bipolar is often treated with lithium... If the\u00a0bipolar lifestyle\u00a0is a rollercoaster ride, then lithium is one of the more established seatbelts available.\u00a0Lithium is considered the\u00a0gold standard\u00a0treatment for bipolar. While it is not as effective in the treatment of acute\u00a0depression, it is very effective for acute\u00a0mania\u00a0as well as for maintaining\u00a0stability. Technically\u00a0lithium\u00a0is\u2026","rel":"","context":"In "All Posts"","block_context":{"text":"All Posts","link":"https:\/\/thetravellerslastjourney.com\/shai\/all-posts\/"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":1779,"url":"https:\/\/thetravellerslastjourney.com\/shai\/2011\/05\/03\/defining-molecular-biology-2\/","url_meta":{"origin":979,"position":3},"title":"Defining molecular biology","author":"Pala","date":"May 3, 2011","format":false,"excerpt":"Editorial notes: This Essay was found as a 'draft' entry in Everything2. It was last updated on 03\/05\/2011. To\u00a0me,\u00a0molecular biology is that part of\u00a0biology\u00a0that is concerned with the\u00a0molecules\u00a0that make up biological systems. It is concerned with those molecules' lives, and the way they interact with each other. It manipulates molecules\u2026","rel":"","context":"In "All Posts"","block_context":{"text":"All Posts","link":"https:\/\/thetravellerslastjourney.com\/shai\/all-posts\/"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":1717,"url":"https:\/\/thetravellerslastjourney.com\/shai\/2010\/11\/24\/line-1-retrotransposition-in-neurons-2\/","url_meta":{"origin":979,"position":4},"title":"LINE-1 retrotransposition in neurons","author":"Pala","date":"November 24, 2010","format":false,"excerpt":"LINE-1\u00a0retrotransposons are sections of\u00a0DNA\u00a0which are capable of copying themselves into another part of the\u00a0genome. Although traditionally considered to merely epitomize the concept of the\u00a0selfish gene, more recently they have been suggested to have physiological functions. Here I discuss the\u00a0incredibly fascinating hypothesis\u00a0that\u00a0LINE-1\u00a0retrotransposons may be important in generating\u00a0neuronal variation. Selfish genes and\u2026","rel":"","context":"In "All Posts"","block_context":{"text":"All Posts","link":"https:\/\/thetravellerslastjourney.com\/shai\/all-posts\/"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":2399,"url":"https:\/\/thetravellerslastjourney.com\/shai\/2012\/07\/21\/phylotypic-stage\/","url_meta":{"origin":979,"position":5},"title":"Phylotypic stage","author":"Pala","date":"July 21, 2012","format":false,"excerpt":"I have two small\u00a0embryos preserved in alcohol, that I forgot to\u00a0label. At present I am unable to determine the genus to which they belong. They may be lizards, small birds, or even mammals. Karl von Baer\u00a0(1828) The changes undergone by a developing\u00a0embryo\u00a0forms an hourglass: early on embryos from different species\u2026","rel":"","context":"In "All Posts"","block_context":{"text":"All Posts","link":"https:\/\/thetravellerslastjourney.com\/shai\/all-posts\/"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]}],"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/padotI-fN","_links":{"self":[{"href":"https:\/\/thetravellerslastjourney.com\/shai\/wp-json\/wp\/v2\/posts\/979","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/thetravellerslastjourney.com\/shai\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/thetravellerslastjourney.com\/shai\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/thetravellerslastjourney.com\/shai\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/thetravellerslastjourney.com\/shai\/wp-json\/wp\/v2\/comments?post=979"}],"version-history":[{"count":0,"href":"https:\/\/thetravellerslastjourney.com\/shai\/wp-json\/wp\/v2\/posts\/979\/revisions"}],"wp:attachment":[{"href":"https:\/\/thetravellerslastjourney.com\/shai\/wp-json\/wp\/v2\/media?parent=979"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/thetravellerslastjourney.com\/shai\/wp-json\/wp\/v2\/categories?post=979"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/thetravellerslastjourney.com\/shai\/wp-json\/wp\/v2\/tags?post=979"},{"taxonomy":"metadata","embeddable":true,"href":"https:\/\/thetravellerslastjourney.com\/shai\/wp-json\/wp\/v2\/metadata?post=979"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}